Early Virulence Predictors during the Candida Species–Galleria mellonella Interaction
نویسندگان
چکیده
منابع مشابه
Examining the virulence of Candida albicans transcription factor mutants using Galleria mellonella and mouse infection models
The aim of the present study was to identify Candida albicans transcription factors (TFs) involved in virulence. Although mice are considered the gold-standard model to study fungal virulence, mini-host infection models have been increasingly used. Here, barcoded TF mutants were first screened in mice by pools of strains and fungal burdens (FBs) quantified in kidneys. Mutants of unannotated gen...
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Candida species are common human fungal pathogens causing a wide range of clinical diseases, ranging from superficial infections to life-threatening systemic disease. Superficial infections include vaginal candidiasis which affects over 75% of women during their lifetime with 5% of women suffering debilitating recurrent infections. Life-threatening systemic Candida disease is the fourth most co...
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Candida spp. are among the most important human fungal pathogens, with infections ranging from relatively benign, superficial manifestation to life-threatening deep-seated candidiasis and disseminated disease. Different mouse models have been developed to recapitulate the different forms of candidiasis and murine models are considered to be the gold standard to study pathogenesis and analyze ef...
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Editorial In many diagnostic microbiology laboratories the species identification process starting from cultured colonies has recently undergone some significant changes. Where not long ago car-bon/nitrogen source utilization tests in the form of colorful tubes or well-based devices down to chip card size dominated the field, we now find a purely biophysical instrument, a MALDI-ToF mass spectro...
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ژورنال
عنوان ژورنال: Journal of Fungi
سال: 2020
ISSN: 2309-608X
DOI: 10.3390/jof6030152